null

SMILES: COc1cccc(CNC(=O)c2cc3cnc(cc3[nH]2)-c2cn[nH]c2)c1

InChI Key: InChIKey=PNQBFFMUTOOPRR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50358473 (CHEMBL1923162) Show SMILES COc1cccc(CNC(=O)c2cc3cnc(cc3[nH]2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H17N5O2/c1-26-15-4-2-3-12(5-15)8-21-19(25)18-6-13-9-20-16(7-17(13)24-18)14-10-22-23-11-14/h2-7,9-11,24H,8H2,1H3,(H,21,25)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 21: 7107-12 (2011) Article DOI: 10.1016/j.bmcl.2011.09.083 BindingDB Entry DOI: 10.7270/Q20002H5
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50358473 (CHEMBL1923162) Show SMILES COc1cccc(CNC(=O)c2cc3cnc(cc3[nH]2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H17N5O2/c1-26-15-4-2-3-12(5-15)8-21-19(25)18-6-13-9-20-16(7-17(13)24-18)14-10-22-23-11-14/h2-7,9-11,24H,8H2,1H3,(H,21,25)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human 6-His-tagged ROCK2 expressed in Sf9 cells				Bioorg Med Chem Lett 21: 7107-12 (2011) Article DOI: 10.1016/j.bmcl.2011.09.083 BindingDB Entry DOI: 10.7270/Q20002H5
					More data for this Ligand-Target Pair