null

SMILES: COc1cccc(CCNC(=O)c2c[nH]c3cc(ccc23)-c2cn[nH]c2)c1

InChI Key: InChIKey=PHOBRHBNCBQQGX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50358489 (CHEMBL1923176) Show SMILES COc1cccc(CCNC(=O)c2c[nH]c3cc(ccc23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C21H20N4O2/c1-27-17-4-2-3-14(9-17)7-8-22-21(26)19-13-23-20-10-15(5-6-18(19)20)16-11-24-25-12-16/h2-6,9-13,23H,7-8H2,1H3,(H,22,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 21: 7107-12 (2011) Article DOI: 10.1016/j.bmcl.2011.09.083 BindingDB Entry DOI: 10.7270/Q20002H5
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50358489 (CHEMBL1923176) Show SMILES COc1cccc(CCNC(=O)c2c[nH]c3cc(ccc23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C21H20N4O2/c1-27-17-4-2-3-14(9-17)7-8-22-21(26)19-13-23-20-10-15(5-6-18(19)20)16-11-24-25-12-16/h2-6,9-13,23H,7-8H2,1H3,(H,22,26)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human 6-His-tagged ROCK2 expressed in Sf9 cells				Bioorg Med Chem Lett 21: 7107-12 (2011) Article DOI: 10.1016/j.bmcl.2011.09.083 BindingDB Entry DOI: 10.7270/Q20002H5
					More data for this Ligand-Target Pair