null

SMILES: NC(=O)c1ccccc1Nc1ccnc(Oc2ccc(cc2)N2CCNCC2)c1

InChI Key: InChIKey=UHNHUQMERWMFSO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50358529 (CHEMBL1923185) Show SMILES NC(=O)c1ccccc1Nc1ccnc(Oc2ccc(cc2)N2CCNCC2)c1 Show InChI InChI=1S/C22H23N5O2/c23-22(28)19-3-1-2-4-20(19)26-16-9-10-25-21(15-16)29-18-7-5-17(6-8-18)27-13-11-24-12-14-27/h1-10,15,24H,11-14H2,(H2,23,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50358529 (CHEMBL1923185) Show SMILES NC(=O)c1ccccc1Nc1ccnc(Oc2ccc(cc2)N2CCNCC2)c1 Show InChI InChI=1S/C22H23N5O2/c23-22(28)19-3-1-2-4-20(19)26-16-9-10-25-21(15-16)29-18-7-5-17(6-8-18)27-13-11-24-12-14-27/h1-10,15,24H,11-14H2,(H2,23,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 using biotinylated-ATF2 as substrate by HTRF assay				Bioorg Med Chem Lett 21: 7072-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.090 BindingDB Entry DOI: 10.7270/Q2V69K0W
					More data for this Ligand-Target Pair