BDBM50358581 CHEMBL1923973
SMILES: CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(n1)C(C)NC(C)=O
InChI Key: InChIKey=HJNOHXBEFNKEHY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50358581 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human)) | BDBM50358581
(CHEMBL1923973)Show SMILES CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(n1)C(C)NC(C)=O Show InChI InChI=1S/C19H21N7O/c1-10(22-11(2)27)13-6-5-7-14(23-13)15-8-12-17-16(21-9-26(17)4)19(20-3)25-18(12)24-15/h5-10H,1-4H3,(H,22,27)(H2,20,24,25) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylation |
Bioorg Med Chem Lett 21: 7006-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.111
BindingDB Entry DOI: 10.7270/Q2Z038KC |
More data for this
Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human)) | BDBM50358581
(CHEMBL1923973)Show SMILES CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(n1)C(C)NC(C)=O Show InChI InChI=1S/C19H21N7O/c1-10(22-11(2)27)13-6-5-7-14(23-13)15-8-12-17-16(21-9-26(17)4)19(20-3)25-18(12)24-15/h5-10H,1-4H3,(H,22,27)(H2,20,24,25) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylation |
Bioorg Med Chem Lett 21: 7006-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.111
BindingDB Entry DOI: 10.7270/Q2Z038KC |
More data for this
Ligand-Target Pair | |
Search and Browse
