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SMILES: CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(NC(C)=O)n1

InChI Key: InChIKey=PFAGWYYLSQHNGI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358599   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inhibitor of nuclear factor kappa-B kinase subunit beta


(Homo sapiens (Human))		BDBM50358599
PNG
(CHEMBL1923990)
Show SMILES CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(NC(C)=O)n1
Show InChI InChI=1S/C17H17N7O/c1-9(25)20-13-6-4-5-11(21-13)12-7-10-15-14(19-8-24(15)3)17(18-2)23-16(10)22-12/h4-8H,1-3H3,(H2,18,22,23)(H,20,21,25)
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Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylation

Bioorg Med Chem Lett 21: 7006-12 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.111
BindingDB Entry DOI: 10.7270/Q2Z038KC
More data for this
Ligand-Target Pair