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SMILES: CC[C@H]1CN(CCN1C1CCN(Cc2ccc(Cl)cc2[C@H](O)C(N)=O)CC1)c1nc(N)c(nc1Cl)C(N)=O

InChI Key: InChIKey=NODKMARWCGQTPH-JXFKEZNVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358625   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50358625
PNG
(CHEMBL1921874)
Show SMILES CC[C@H]1CN(CCN1C1CCN(Cc2ccc(Cl)cc2[C@H](O)C(N)=O)CC1)c1nc(N)c(nc1Cl)C(N)=O |r|
Show InChI InChI=1S/C25H34Cl2N8O3/c1-2-16-13-34(25-21(27)31-19(23(29)37)22(28)32-25)9-10-35(16)17-5-7-33(8-6-17)12-14-3-4-15(26)11-18(14)20(36)24(30)38/h3-4,11,16-17,20,36H,2,5-10,12-13H2,1H3,(H2,28,32)(H2,29,37)(H2,30,38)/t16-,20-/m0/s1
UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem

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Article
PubMed
n/an/a 4.10n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cells

Bioorg Med Chem Lett 21: 6982-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.120
BindingDB Entry DOI: 10.7270/Q2T72HVN
More data for this
Ligand-Target Pair