BDBM50358742 CHEMBL1922269

SMILES: C[C@@H]1[C@H]2CN(CCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F

InChI Key: InChIKey=ZJWXPPLSZFSNGB-WRWLIDTKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50358742 (CHEMBL1922269) Show SMILES C[C@@H]1[C@H]2CN(CCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F |r| Show InChI InChI=1S/C24H31F3N2O/c1-15-20-14-29(8-4-16-6-10-30-11-7-16)9-5-17(20)12-22-23(15)19-13-18(24(25,26)27)2-3-21(19)28-22/h2-3,13,15-17,20,28H,4-12,14H2,1H3/t15-,17-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from MCHR1 after 2 hrs by beta scintillation counting				Bioorg Med Chem Lett 21: 7001-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.110 BindingDB Entry DOI: 10.7270/Q29887FX
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50358742 (CHEMBL1922269) Show SMILES C[C@@H]1[C@H]2CN(CCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F |r| Show InChI InChI=1S/C24H31F3N2O/c1-15-20-14-29(8-4-16-6-10-30-11-7-16)9-5-17(20)12-22-23(15)19-13-18(24(25,26)27)2-3-21(19)28-22/h2-3,13,15-17,20,28H,4-12,14H2,1H3/t15-,17-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in Jurkat cells co-expressing apoaequorin assessed as inhibition of MCH-induced calcium mobilization by ...				Bioorg Med Chem Lett 21: 7001-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.110 BindingDB Entry DOI: 10.7270/Q29887FX
					More data for this Ligand-Target Pair