null

SMILES: CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc2cc(OC)ccc2c1

InChI Key: InChIKey=FDJJIEIXVPODKX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50358800 (CHEMBL1922927) Show SMILES CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc2cc(OC)ccc2c1 Show InChI InChI=1S/C35H33ClN2O5/c1-3-4-26(17-22-5-7-23(8-6-22)35(42)37-16-15-33(39)40)34(41)32-21-27-18-28(36)11-14-31(27)38(32)29-12-9-25-20-30(43-2)13-10-24(25)19-29/h5-14,18-21,26H,3-4,15-17H2,1-2H3,(H,37,42)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by scintillation proximity assay				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358800 (CHEMBL1922927) Show SMILES CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc2cc(OC)ccc2c1 Show InChI InChI=1S/C35H33ClN2O5/c1-3-4-26(17-22-5-7-23(8-6-22)35(42)37-16-15-33(39)40)34(41)32-21-27-18-28(36)11-14-31(27)38(32)29-12-9-25-20-30(43-2)13-10-24(25)19-29/h5-14,18-21,26H,3-4,15-17H2,1-2H3,(H,37,42)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor expressed in CHO cells assessed as inhibition of forskolin/glucagon-induced cAMP production preincubat...				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair