null

SMILES: CCCCC[C@@H](Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(ccc2n1-c1cccc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=QLEJNCAOFVEXSA-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50358811 (CHEMBL1922939) Show SMILES CCCCC[C@@H](Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(ccc2n1-c1cccc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C34H32F6N2O4/c1-2-3-4-6-23(17-21-9-11-22(12-10-21)32(46)41-16-15-30(43)44)31(45)29-19-24-18-26(34(38,39)40)13-14-28(24)42(29)27-8-5-7-25(20-27)33(35,36)37/h5,7-14,18-20,23H,2-4,6,15-17H2,1H3,(H,41,46)(H,43,44)/t23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor expressed in CHO cells assessed as inhibition of forskolin/glucagon-induced cAMP production preincubat...				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358811 (CHEMBL1922939) Show SMILES CCCCC[C@@H](Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(ccc2n1-c1cccc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C34H32F6N2O4/c1-2-3-4-6-23(17-21-9-11-22(12-10-21)32(46)41-16-15-30(43)44)31(45)29-19-24-18-26(34(38,39)40)13-14-28(24)42(29)27-8-5-7-25(20-27)33(35,36)37/h5,7-14,18-20,23H,2-4,6,15-17H2,1H3,(H,41,46)(H,43,44)/t23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by scintillation proximity assay				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair