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BDBM50359234 CHEMBL1923624

SMILES: C[C@H]1N(C)C(=O)[C@@H](NCCOc2ccccc2CCCNC(=O)[C@@H](Cc2cccc(F)c2)NC1=O)C1CC1

InChI Key: InChIKey=ADIOQAYPSGHDFT-OXTYCOSGSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359234   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Appetite-regulating hormone


(Homo sapiens (Human))		BDBM50359234
PNG
(CHEMBL1923624)
Show SMILES C[C@H]1N(C)C(=O)[C@@H](NCCOc2ccccc2CCCNC(=O)[C@@H](Cc2cccc(F)c2)NC1=O)C1CC1 |r|
Show InChI InChI=1S/C29H37FN4O4/c1-19-27(35)33-24(18-20-7-5-10-23(30)17-20)28(36)32-14-6-9-21-8-3-4-11-25(21)38-16-15-31-26(22-12-13-22)29(37)34(19)2/h3-5,7-8,10-11,17,19,22,24,26,31H,6,9,12-16,18H2,1-2H3,(H,32,36)(H,33,35)/t19-,24-,26+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
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PC sid
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Similars
Article
PubMed
 21n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assay

J Med Chem 54: 8305-20 (2011)


Article DOI: 10.1021/jm2007062
BindingDB Entry DOI: 10.7270/Q2930TK0
More data for this
Ligand-Target Pair