BDBM50359236 CHEMBL1923626
SMILES: C[C@H]1N(C)C(=O)[C@@H](NCCOc2ccccc2CCCNC(=O)[C@@H](Cc2ccc(cc2)C(F)(F)F)NC1=O)C1CC1
InChI Key: InChIKey=UMRFQLWVRFCHER-OXTYCOSGSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Appetite-regulating hormone (Homo sapiens (Human)) | BDBM50359236 (CHEMBL1923626) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc. Curated by ChEMBL | Assay Description Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assay | J Med Chem 54: 8305-20 (2011) Article DOI: 10.1021/jm2007062 BindingDB Entry DOI: 10.7270/Q2930TK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Appetite-regulating hormone (Homo sapiens (Human)) | BDBM50359236 (CHEMBL1923626) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Tranzyme Pharma Inc. Curated by ChEMBL | Assay Description Agonist activity at human GRLN receptor expressed in HEK293 cells assessed as calcium binding by Ca2+ bioluminescence aequorin assay | J Med Chem 54: 8305-20 (2011) Article DOI: 10.1021/jm2007062 BindingDB Entry DOI: 10.7270/Q2930TK0 | |||||||||||
More data for this Ligand-Target Pair |