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BDBM50359253 CHEMBL1923643

SMILES: C[C@H]1N(C)C(=O)[C@@H](NCCOc2ccc(F)cc2CCCNC(=O)[C@@H](Cc2ccc(F)cc2)NC1=O)C1CC1

InChI Key: InChIKey=IJYGTBLRLXLFBP-UFKXBGGNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359253   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Appetite-regulating hormone


(Homo sapiens (Human))		BDBM50359253
PNG
(CHEMBL1923643)
Show SMILES C[C@H]1N(C)C(=O)[C@@H](NCCOc2ccc(F)cc2CCCNC(=O)[C@@H](Cc2ccc(F)cc2)NC1=O)C1CC1 |r|
Show InChI InChI=1S/C29H36F2N4O4/c1-18-27(36)34-24(16-19-5-9-22(30)10-6-19)28(37)33-13-3-4-21-17-23(31)11-12-25(21)39-15-14-32-26(20-7-8-20)29(38)35(18)2/h5-6,9-12,17-18,20,24,26,32H,3-4,7-8,13-16H2,1-2H3,(H,33,37)(H,34,36)/t18-,24-,26+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 58n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assay

J Med Chem 54: 8305-20 (2011)


Article DOI: 10.1021/jm2007062
BindingDB Entry DOI: 10.7270/Q2930TK0
More data for this
Ligand-Target Pair