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SMILES: CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)c(s1)C(=O)N1CCS(=O)(=O)CC1

InChI Key: InChIKey=XRNFMZFFBWORHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359322   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50359322
PNG
(CHEMBL1929201)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)c(s1)C(=O)N1CCS(=O)(=O)CC1
Show InChI InChI=1S/C24H27N3O4S2/c1-24(2,3)20-15-19(21(32-20)22(28)27-11-13-33(30,31)14-12-27)26-23(29)25-18-10-6-8-16-7-4-5-9-17(16)18/h4-10,15H,11-14H2,1-3H3,(H2,25,26,29)
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n/an/a 130n/an/an/an/an/an/a



Ansaris

Curated by ChEMBL


Assay Description
Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into GST-ATF2 substrate preincubated for 20 mins before substrate addition measured a...

Bioorg Med Chem Lett 21: 7155-65 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.078
BindingDB Entry DOI: 10.7270/Q2NC61NH
More data for this
Ligand-Target Pair