BDBM50359370 CHEMBL1929391

SMILES: Cc1c(cnc2cc(nn12)C(C)(C)C)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=ONEZBKYGJZWXCN-INIZCTEOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50359370 (CHEMBL1929391) Show SMILES Cc1c(cnc2cc(nn12)C(C)(C)C)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C23H33N7O2/c1-15-17(12-25-19-10-18(22(2,3)4)28-30(15)19)21(32)26-14-23(5,6)27-13-20(31)29-9-7-8-16(29)11-24/h10,12,16,27H,7-9,13-14H2,1-6H3,(H,26,32)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-4 using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50359370 (CHEMBL1929391) Show SMILES Cc1c(cnc2cc(nn12)C(C)(C)C)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C23H33N7O2/c1-15-17(12-25-19-10-18(22(2,3)4)28-30(15)19)21(32)26-14-23(5,6)27-13-20(31)29-9-7-8-16(29)11-24/h10,12,16,27H,7-9,13-14H2,1-6H3,(H,26,32)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-9 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50359370 (CHEMBL1929391) Show SMILES Cc1c(cnc2cc(nn12)C(C)(C)C)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C23H33N7O2/c1-15-17(12-25-19-10-18(22(2,3)4)28-30(15)19)21(32)26-14-23(5,6)27-13-20(31)29-9-7-8-16(29)11-24/h10,12,16,27H,7-9,13-14H2,1-6H3,(H,26,32)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair