BDBM50359372 CHEMBL1929393

SMILES: Cc1nc2cc(nn2c(C)c1C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N)C(C)(C)C

InChI Key: InChIKey=YIDAVMZDHIDPFB-KRWDZBQOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50359372 (CHEMBL1929393) Show SMILES Cc1nc2cc(nn2c(C)c1C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N)C(C)(C)C |r| Show InChI InChI=1S/C24H35N7O2/c1-15-21(16(2)31-19(28-15)11-18(29-31)23(3,4)5)22(33)26-14-24(6,7)27-13-20(32)30-10-8-9-17(30)12-25/h11,17,27H,8-10,13-14H2,1-7H3,(H,26,33)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-4 using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50359372 (CHEMBL1929393) Show SMILES Cc1nc2cc(nn2c(C)c1C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N)C(C)(C)C |r| Show InChI InChI=1S/C24H35N7O2/c1-15-21(16(2)31-19(28-15)11-18(29-31)23(3,4)5)22(33)26-14-24(6,7)27-13-20(32)30-10-8-9-17(30)12-25/h11,17,27H,8-10,13-14H2,1-7H3,(H,26,33)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-9 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50359372 (CHEMBL1929393) Show SMILES Cc1nc2cc(nn2c(C)c1C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N)C(C)(C)C |r| Show InChI InChI=1S/C24H35N7O2/c1-15-21(16(2)31-19(28-15)11-18(29-31)23(3,4)5)22(33)26-14-24(6,7)27-13-20(32)30-10-8-9-17(30)12-25/h11,17,27H,8-10,13-14H2,1-7H3,(H,26,33)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair