null

SMILES: Nc1nc2ccccc2nc1NCCOc1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=RYDVGAFXMZFSBM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50359382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50359382 (CHEMBL1929406) Show SMILES Nc1nc2ccccc2nc1NCCOc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C22H27N5O/c23-21-22(26-20-7-3-2-6-19(20)25-21)24-12-15-28-18-10-8-17(9-11-18)16-27-13-4-1-5-14-27/h2-3,6-11H,1,4-5,12-16H2,(H2,23,25)(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at histamine H3 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamin...				Bioorg Med Chem 19: 7158-67 (2011) Article DOI: 10.1016/j.bmc.2011.09.061 BindingDB Entry DOI: 10.7270/Q24F1R52
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50359382 (CHEMBL1929406) Show SMILES Nc1nc2ccccc2nc1NCCOc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C22H27N5O/c23-21-22(26-20-7-3-2-6-19(20)25-21)24-12-15-28-18-10-8-17(9-11-18)16-27-13-4-1-5-14-27/h2-3,6-11H,1,4-5,12-16H2,(H2,23,25)(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide as substrate after 15 mins by Ellman's method				Bioorg Med Chem 19: 7158-67 (2011) Article DOI: 10.1016/j.bmc.2011.09.061 BindingDB Entry DOI: 10.7270/Q24F1R52
					More data for this Ligand-Target Pair