BDBM50359411 CHEMBL1926723

SMILES: CCOC(=O)Nc1cc(NCCN(C)C)c2nc(-c3ccco3)c(nc2n1)-c1ccco1

InChI Key: InChIKey=YDKOUYRZFYPLEM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Mycobacterium tuberculosis)	BDBM50359411 (CHEMBL1926723) Show SMILES CCOC(=O)Nc1cc(NCCN(C)C)c2nc(-c3ccco3)c(nc2n1)-c1ccco1 Show InChI InChI=1S/C22H24N6O4/c1-4-30-22(29)25-17-13-14(23-9-10-28(2)3)18-21(24-17)27-20(16-8-6-12-32-16)19(26-18)15-7-5-11-31-15/h5-8,11-13H,4,9-10H2,1-3H3,(H2,23,24,25,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay				Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1
					More data for this Ligand-Target Pair