BDBM50359554 CHEMBL1927473

SMILES: Cc1nc(sc1CSc1ccc(OC(F)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=AHNGEGAQWSRCBH-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50359554 (CHEMBL1927473) Show SMILES Cc1nc(sc1CSc1ccc(OC(F)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F4NO3S2/c1-11-9-15(7-8-16(11)29-18(22)20(27)28)30-10-17-12(2)26-19(31-17)13-3-5-14(6-4-13)21(23,24)25/h3-9,18H,10H2,1-2H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 after 24 hrs by luciferase reporter gene ...				Bioorg Med Chem 19: 6982-8 (2011) Article DOI: 10.1016/j.bmc.2011.10.020 BindingDB Entry DOI: 10.7270/Q2FQ9X2C
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50359554 (CHEMBL1927473) Show SMILES Cc1nc(sc1CSc1ccc(OC(F)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F4NO3S2/c1-11-9-15(7-8-16(11)29-18(22)20(27)28)30-10-17-12(2)26-19(31-17)13-3-5-14(6-4-13)21(23,24)25/h3-9,18H,10H2,1-2H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in COS-1 cells after 24 hrs by luciferase reporter gene-based luminometeric analy...				Bioorg Med Chem 19: 6982-8 (2011) Article DOI: 10.1016/j.bmc.2011.10.020 BindingDB Entry DOI: 10.7270/Q2FQ9X2C
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50359554 (CHEMBL1927473) Show SMILES Cc1nc(sc1CSc1ccc(OC(F)C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F4NO3S2/c1-11-9-15(7-8-16(11)29-18(22)20(27)28)30-10-17-12(2)26-19(31-17)13-3-5-14(6-4-13)21(23,24)25/h3-9,18H,10H2,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells after 24 hrs by luciferase reporter gene-based luminometeric analy...				Bioorg Med Chem 19: 6982-8 (2011) Article DOI: 10.1016/j.bmc.2011.10.020 BindingDB Entry DOI: 10.7270/Q2FQ9X2C
					More data for this Ligand-Target Pair