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BDBM50359615 CHEMBL1928220

SMILES: O[C@@H](CC1CCCCC1)\C=C\[C@H]1[C@H](O)C[C@@H]2Oc3c(cccc3CCc3nnn[nH]3)[C@H]12

InChI Key: InChIKey=VLFOPQQEYFUEHI-PQEHKDGBSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359615   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Oryctolagus cuniculus)		BDBM50359615
PNG
(CHEMBL1928220)
Show SMILES O[C@@H](CC1CCCCC1)\C=C\[C@H]1[C@H](O)C[C@@H]2Oc3c(cccc3CCc3nnn[nH]3)[C@H]12 |r|
Show InChI InChI=1S/C24H32N4O3/c29-17(13-15-5-2-1-3-6-15)10-11-18-20(30)14-21-23(18)19-8-4-7-16(24(19)31-21)9-12-22-25-27-28-26-22/h4,7-8,10-11,15,17-18,20-21,23,29-30H,1-3,5-6,9,12-14H2,(H,25,26,27,28)/b11-10+/t17-,18+,20-,21+,23+/m1/s1
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/an/an/a 2.60n/an/an/an/a



Toray Industries, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rabbit EP4 receptor assessed as relaxation of Kcl-induced tissue contraction by isometric transducer method

Bioorg Med Chem Lett 21: 7505-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.004
BindingDB Entry DOI: 10.7270/Q2SX6DNT
More data for this
Ligand-Target Pair