BDBM50359903 CHEMBL409502
SMILES: O=C1N\C(S\C1=C/c1ccccc1)=N\c1nsc2ccccc12
InChI Key: InChIKey=SFZMBRAWNOHSKH-UVTDQMKNSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep)) | BDBM50359903 (CHEMBL409502) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Alexander Technological Education Institute of Thessaloniki Curated by ChEMBL | Assay Description Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay | Eur J Med Chem 47: 111-24 (2012) Article DOI: 10.1016/j.ejmech.2011.10.029 BindingDB Entry DOI: 10.7270/Q2K937ZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50359903 (CHEMBL409502) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Catania Curated by ChEMBL | Assay Description Inhibition of MMP13 catalytic domain (unknown origin) assessed as reduction in hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured f... | Bioorg Med Chem 23: 1551-6 (2015) Article DOI: 10.1016/j.bmc.2015.02.002 BindingDB Entry DOI: 10.7270/Q26T0P92 | |||||||||||
More data for this Ligand-Target Pair |