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BDBM50360252 CHEMBL1928346

SMILES: CN(C)CCCNc1nc(nc(n1)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=UCQUJNSURCNKTH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360252   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vanilloid receptor


(Rattus norvegicus (rat))		BDBM50360252
PNG
(CHEMBL1928346)
Show SMILES CN(C)CCCNc1nc(nc(n1)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1)N1CCN(CC1)C(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C42H47F4N9/c1-51(2)21-3-20-47-40-48-41(54-26-22-52(23-27-54)38(30-4-12-34(43)13-5-30)31-6-14-35(44)15-7-31)50-42(49-40)55-28-24-53(25-29-55)39(32-8-16-36(45)17-9-32)33-10-18-37(46)19-11-33/h4-19,38-39H,3,20-29H2,1-2H3,(H,47,48,49,50)
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PC cid
PC sid
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Article
PubMed
n/an/a 5.64E+4n/an/an/an/an/an/a



Institut de Qu£mica Avan£ada de Catalunya

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV1 expressed in Xenopus laevis oocytes assessed as blockage of capsaicin-induced current at holding potential -60 mV by...

J Med Chem 54: 7441-52 (2011)


Article DOI: 10.1021/jm200981s
BindingDB Entry DOI: 10.7270/Q2M32W6F
More data for this
Ligand-Target Pair