BDBM50360267 CHEMBL1928212

SMILES: NCCN1CCN(CC1)c1nc(NCCc2ccc(Cl)cc2)nc(NCCc2ccc(Cl)cc2)n1

InChI Key: InChIKey=GXLWKHKZDXOSPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50360267 (CHEMBL1928212) Show SMILES NCCN1CCN(CC1)c1nc(NCCc2ccc(Cl)cc2)nc(NCCc2ccc(Cl)cc2)n1 Show InChI InChI=1S/C25H32Cl2N8/c26-21-5-1-19(2-6-21)9-12-29-23-31-24(30-13-10-20-3-7-22(27)8-4-20)33-25(32-23)35-17-15-34(14-11-28)16-18-35/h1-8H,9-18,28H2,(H2,29,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Qu£mica Avan£ada de Catalunya Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in Xenopus laevis oocytes assessed as blockage of capsaicin-induced current at holding potential -60 mV by...				J Med Chem 54: 7441-52 (2011) Article DOI: 10.1021/jm200981s BindingDB Entry DOI: 10.7270/Q2M32W6F
					More data for this Ligand-Target Pair