BDBM50360604 CHEMBL1933537

SMILES: Clc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNCC2)c2ccccc12

InChI Key: InChIKey=RNBXCZIGHFUUSQ-RUZDIDTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Syk protein (Mus musculus)	BDBM50360604 (CHEMBL1933537) Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNCC2)c2ccccc12 |r| Show InChI InChI=1S/C25H27ClN4O/c26-18-5-6-21-17(13-18)14-22(28-21)24(31)30-16-25(20-3-1-2-4-23(20)30)9-12-29(15-25)19-7-10-27-11-8-19/h1-6,13-14,19,27-28H,7-12,15-16H2/t25-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA				Bioorg Med Chem Lett 22: 190-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.036 BindingDB Entry DOI: 10.7270/Q2CF9QJS
					More data for this Ligand-Target Pair