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BDBM50360606 CHEMBL1933539

SMILES: Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CNC2)c2ccccc12

InChI Key: InChIKey=XPHCAEDIXCJNLS-HSZRJFAPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Syk protein


(Mus musculus)
BDBM50360606
PNG
(CHEMBL1933539)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CNC2)c2ccccc12 |r|
Show InChI InChI=1S/C23H23FN4O/c24-16-5-6-19-15(9-16)10-20(26-19)22(29)28-14-23(18-3-1-2-4-21(18)28)7-8-27(13-23)17-11-25-12-17/h1-6,9-10,17,25-26H,7-8,11-14H2/t23-/m1/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.81E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA


Bioorg Med Chem Lett 22: 190-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.036
BindingDB Entry DOI: 10.7270/Q2CF9QJS
More data for this
Ligand-Target Pair