BDBM50360638 CHEMBL1933734

SMILES: CC1(C)Cc2nn(c(c2C(=O)C1)-c1ccc(Cl)c(Cl)c1)-c1ccc(O)cc1

InChI Key: InChIKey=OTPCBZYHHUHVRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50360638 (CHEMBL1933734) Show SMILES CC1(C)Cc2nn(c(c2C(=O)C1)-c1ccc(Cl)c(Cl)c1)-c1ccc(O)cc1 Show InChI InChI=1S/C21H18Cl2N2O2/c1-21(2)10-17-19(18(27)11-21)20(12-3-8-15(22)16(23)9-12)25(24-17)13-4-6-14(26)7-5-13/h3-9,26H,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...				Bioorg Med Chem Lett 22: 410-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.124 BindingDB Entry DOI: 10.7270/Q23X872P
					More data for this Ligand-Target Pair