BDBM50360639 CHEMBL1933735

SMILES: CC1(C)Cc2nn(-c3ccc[nH]3)c(c2C(=O)C1)-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=HLWPJABBWPGCTP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50360639 (CHEMBL1933735) Show SMILES CC1(C)Cc2nn(-c3ccc[nH]3)c(c2C(=O)C1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl2N3O/c1-19(2)9-14-17(15(25)10-19)18(11-5-6-12(20)13(21)8-11)24(23-14)16-4-3-7-22-16/h3-8,22H,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...				Bioorg Med Chem Lett 22: 410-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.124 BindingDB Entry DOI: 10.7270/Q23X872P
					More data for this Ligand-Target Pair