BDBM50360640 CHEMBL1933736

SMILES: COc1ccc(cc1)-n1nc2CC(C)(C)CC(=O)c2c1-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VNUYCNZSSAYKPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50360640 (CHEMBL1933736) Show SMILES COc1ccc(cc1)-n1nc2CC(C)(C)CC(=O)c2c1-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H20Cl2N2O2/c1-22(2)11-18-20(19(27)12-22)21(13-4-9-16(23)17(24)10-13)26(25-18)14-5-7-15(28-3)8-6-14/h4-10H,11-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...				Bioorg Med Chem Lett 22: 410-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.124 BindingDB Entry DOI: 10.7270/Q23X872P
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