BDBM50360655 CHEMBL1933750

SMILES: Cc1ccc(cc1Cl)-c1c2c(CC(C)(C)CC2=O)nn1-c1ccc[nH]1

InChI Key: InChIKey=UXBAPGGYJMNERJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50360655 (CHEMBL1933750) Show SMILES Cc1ccc(cc1Cl)-c1c2c(CC(C)(C)CC2=O)nn1-c1ccc[nH]1 Show InChI InChI=1S/C20H20ClN3O/c1-12-6-7-13(9-14(12)21)19-18-15(10-20(2,3)11-16(18)25)23-24(19)17-5-4-8-22-17/h4-9,22H,10-11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...				Bioorg Med Chem Lett 22: 410-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.124 BindingDB Entry DOI: 10.7270/Q23X872P
					More data for this Ligand-Target Pair