BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cc1OC)-n1nc2CC(C)(C)CC(=O)c2c1-c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=SNJYVXOJETXHLV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360662   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50360662
PNG
(CHEMBL1933757)
Show SMILES COc1ccc(cc1OC)-n1nc2CC(C)(C)CC(=O)c2c1-c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C27H32N2O3/c1-26(2,3)18-10-8-17(9-11-18)25-24-20(15-27(4,5)16-21(24)30)28-29(25)19-12-13-22(31-6)23(14-19)32-7/h8-14H,15-16H2,1-7H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.50E+5n/an/an/an/an/an/a



Birla Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...

Bioorg Med Chem Lett 22: 410-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.124
BindingDB Entry DOI: 10.7270/Q23X872P
More data for this
Ligand-Target Pair