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SMILES: CS(=O)(=O)n1c2ccccc2c2cc(CN3CCC4(CC3)C=Cc3ccccc43)ccc12

InChI Key: InChIKey=QFVOAKYOLSAVBQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360693   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360693
PNG
(CHEMBL1934111)
Show SMILES CS(=O)(=O)n1c2ccccc2c2cc(CN3CCC4(CC3)C=Cc3ccccc43)ccc12 |c:23|
Show InChI InChI=1S/C27H26N2O2S/c1-32(30,31)29-25-9-5-3-7-22(25)23-18-20(10-11-26(23)29)19-28-16-14-27(15-17-28)13-12-21-6-2-4-8-24(21)27/h2-13,18H,14-17,19H2,1H3
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n/an/a 200n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair