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SMILES: CC(=O)N[C@@H]1[C@@H](O)C2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c2ccccc12

InChI Key: InChIKey=GTUCOPXBGYZNQP-RRPNLBNLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360706   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360706
PNG
(CHEMBL1934125)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c2ccccc12 |r|
Show InChI InChI=1S/C28H29N3O2/c1-18(32)29-26-21-7-2-4-8-23(21)28(27(26)33)12-14-31(15-13-28)17-19-10-11-25-22(16-19)20-6-3-5-9-24(20)30-25/h2-11,16,26-27,30,33H,12-15,17H2,1H3,(H,29,32)/t26-,27+/m0/s1
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Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair