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SMILES: CC(=O)Nc1cccc(c1)C1CCN(CCCn2nc(c(C)c(C)c2=O)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=HJBHPJMKFHURAF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360834   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50360834
PNG
(CHEMBL1934812)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCn2nc(c(C)c(C)c2=O)-c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C28H33ClN4O2/c1-19-20(2)28(35)33(31-27(19)23-8-10-25(29)11-9-23)15-5-14-32-16-12-22(13-17-32)24-6-4-7-26(18-24)30-21(3)34/h4,6-11,18,22H,5,12-17H2,1-3H3,(H,30,34)
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Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of Eu-MCH from human recombinant MCH-R1 expressed in CHO cell membrane after 90 mins by time-resolved fluorescence assay

Bioorg Med Chem Lett 22: 427-30 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.111
BindingDB Entry DOI: 10.7270/Q2F76D09
More data for this
Ligand-Target Pair