BDBM50360951 CHEMBL1935299

SMILES: CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)-c1noc(n1)C(F)(F)F)C(O)=O

InChI Key: InChIKey=XOJQSQYURGQXNG-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50360951 (CHEMBL1935299) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)-c1noc(n1)C(F)(F)F)C(O)=O |r| Show InChI InChI=1S/C20H16F3N3O6S/c1-9(2)16(18(27)28)26-33(29,30)11-4-5-12-13-7-10(3-6-14(13)31-15(12)8-11)17-24-19(32-25-17)20(21,22)23/h3-9,16,26H,1-2H3,(H,27,28)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human MMP-12				Bioorg Med Chem Lett 22: 138-43 (2011) Article DOI: 10.1016/j.bmcl.2011.11.046 BindingDB Entry DOI: 10.7270/Q2SJ1M20
					More data for this Ligand-Target Pair