Found 3 hits for monomerid = 50360996 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50360996
(CHEMBL1935433)Show SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(CC(=O)N3CCCCC3)C2)cc1 Show InChI InChI=1S/C26H31FN4O/c27-22-12-10-20(11-13-22)17-31-24-9-3-2-8-23(24)28-26(31)21-7-6-14-29(18-21)19-25(32)30-15-4-1-5-16-30/h2-3,8-13,21H,1,4-7,14-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H1 receptor |
Bioorg Med Chem Lett 22: 421-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.115 BindingDB Entry DOI: 10.7270/Q2J103KS |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50360996
(CHEMBL1935433)Show SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(CC(=O)N3CCCCC3)C2)cc1 Show InChI InChI=1S/C26H31FN4O/c27-22-12-10-20(11-13-22)17-31-24-9-3-2-8-23(24)28-26(31)21-7-6-14-29(18-21)19-25(32)30-15-4-1-5-16-30/h2-3,8-13,21H,1,4-7,14-19H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences
Curated by ChEMBL
| Assay Description Displacement of [3H]dofetolide from human Erg |
Bioorg Med Chem Lett 22: 421-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.115 BindingDB Entry DOI: 10.7270/Q2J103KS |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50360996
(CHEMBL1935433)Show SMILES Fc1ccc(Cn2c(nc3ccccc23)C2CCCN(CC(=O)N3CCCCC3)C2)cc1 Show InChI InChI=1S/C26H31FN4O/c27-22-12-10-20(11-13-22)17-31-24-9-3-2-8-23(24)28-26(31)21-7-6-14-29(18-21)19-25(32)30-15-4-1-5-16-30/h2-3,8-13,21H,1,4-7,14-19H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 22: 421-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.115 BindingDB Entry DOI: 10.7270/Q2J103KS |
More data for this Ligand-Target Pair | |