BDBM50361023 CHEMBL1935559

SMILES: CN1CCN(CC1)c1nc(N)nc2c(cccc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=PTDJWQPNFNQWFW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50361023 (CHEMBL1935559) Show SMILES CN1CCN(CC1)c1nc(N)nc2c(cccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H20N6/c1-25-9-11-26(12-10-25)19-17-4-2-3-16(18(17)23-20(22)24-19)15-7-5-14(13-21)6-8-15/h2-8H,9-12H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes				Bioorg Med Chem Lett 22: 461-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.104 BindingDB Entry DOI: 10.7270/Q2D79BT2
					More data for this Ligand-Target Pair