BDBM50361025 CHEMBL1935561

SMILES: CN1CCN(CC1)c1nc(N)nc2c(cccc12)-c1cccc(c1)C(C)=O

InChI Key: InChIKey=DSTNEAOJRGCBHS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50361025 (CHEMBL1935561) Show SMILES CN1CCN(CC1)c1nc(N)nc2c(cccc12)-c1cccc(c1)C(C)=O Show InChI InChI=1S/C21H23N5O/c1-14(27)15-5-3-6-16(13-15)17-7-4-8-18-19(17)23-21(22)24-20(18)26-11-9-25(2)10-12-26/h3-8,13H,9-12H2,1-2H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes				Bioorg Med Chem Lett 22: 461-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.104 BindingDB Entry DOI: 10.7270/Q2D79BT2
					More data for this Ligand-Target Pair