BDBM50361193 CHEMBL1934324

SMILES: CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)NC5CC5)cc4)ncnc3c2)CC1

InChI Key: InChIKey=VQOCZYLBCXJOCL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50361193 (CHEMBL1934324) Show SMILES CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)NC5CC5)cc4)ncnc3c2)CC1 Show InChI InChI=1S/C25H30N6O2/c1-31-12-10-17(11-13-31)15-33-21-8-9-22-23(14-21)26-16-27-24(22)28-18-2-4-19(5-3-18)29-25(32)30-20-6-7-20/h2-5,8-9,14,16-17,20H,6-7,10-13,15H2,1H3,(H,26,27,28)(H2,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 22: 110-4 (2011) Article DOI: 10.1016/j.bmcl.2011.11.061 BindingDB Entry DOI: 10.7270/Q2H132FD
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