BDBM50361442 CHEMBL1934407

SMILES: Nc1nc2n(CC(O)COCP(O)(O)=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=OGWFSFLFEFQHOH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50361442 (CHEMBL1934407) Show SMILES Nc1nc2n(CC(O)COCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C9H14N5O6P/c10-9-12-7-6(8(16)13-9)11-3-14(7)1-5(15)2-20-4-21(17,18)19/h3,5,15H,1-2,4H2,(H2,17,18,19)(H3,10,12,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric analysis in absence of PPi				Bioorg Med Chem 20: 1222-30 (2012) Article DOI: 10.1016/j.bmc.2011.12.034 BindingDB Entry DOI: 10.7270/Q25M665C
					More data for this Ligand-Target Pair