BDBM50361491 CHEMBL1939112

SMILES: C[C@@H](CO)Nc1cc2NC(=O)CCc2cc1S(=O)(=O)Nc1ccc(C)c(Cl)c1

InChI Key: InChIKey=VLRYVDZPCCVRIS-LBPRGKRZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase (PKM2) (Homo sapiens (Human))	BDBM50361491 (CHEMBL1939112) Show SMILES C[C@@H](CO)Nc1cc2NC(=O)CCc2cc1S(=O)(=O)Nc1ccc(C)c(Cl)c1 |r| Show InChI InChI=1S/C19H22ClN3O4S/c1-11-3-5-14(8-15(11)20)23-28(26,27)18-7-13-4-6-19(25)22-16(13)9-17(18)21-12(2)10-24/h3,5,7-9,12,21,23-24H,4,6,10H2,1-2H3,(H,22,25)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay				Bioorg Med Chem Lett 21: 6322-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.114 BindingDB Entry DOI: 10.7270/Q28C9WQG
					More data for this Ligand-Target Pair