BDBM50361512 CHEMBL1939090

SMILES: Cc1cc(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)ccc1F

InChI Key: InChIKey=LPVLUUBCUWKBJT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase (PKM2) (Homo sapiens (Human))	BDBM50361512 (CHEMBL1939090) Show SMILES Cc1cc(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)ccc1F Show InChI InChI=1S/C16H15FN2O3S/c1-10-8-12(3-5-14(10)17)19-23(21,22)13-4-6-15-11(9-13)2-7-16(20)18-15/h3-6,8-9,19H,2,7H2,1H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay				Bioorg Med Chem Lett 21: 6322-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.114 BindingDB Entry DOI: 10.7270/Q28C9WQG
					More data for this Ligand-Target Pair