Found 3 hits for monomerid = 50361564 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50361564
(CHEMBL1939491)Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@@H](CC3(C)C)NC(=O)N3CCCC3)c2)ncc1Cl |r| Show InChI InChI=1S/C29H32ClFN8O3/c1-29(2)14-22(36-28(42)39-11-4-5-12-39)26(41)35-21-13-16(9-10-18(21)29)34-27-33-15-19(30)24(38-27)37-23-17(25(40)32-3)7-6-8-20(23)31/h6-10,13,15,22H,4-5,11-12,14H2,1-3H3,(H,32,40)(H,35,41)(H,36,42)(H2,33,34,37,38)/t22-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay |
Bioorg Med Chem 19: 6274-84 (2011)
Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50361564
(CHEMBL1939491)Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@@H](CC3(C)C)NC(=O)N3CCCC3)c2)ncc1Cl |r| Show InChI InChI=1S/C29H32ClFN8O3/c1-29(2)14-22(36-28(42)39-11-4-5-12-39)26(41)35-21-13-16(9-10-18(21)29)34-27-33-15-19(30)24(38-27)37-23-17(25(40)32-3)7-6-8-20(23)31/h6-10,13,15,22H,4-5,11-12,14H2,1-3H3,(H,32,40)(H,35,41)(H,36,42)(H2,33,34,37,38)/t22-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay |
Bioorg Med Chem 19: 6274-84 (2011)
Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50361564
(CHEMBL1939491)Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@@H](CC3(C)C)NC(=O)N3CCCC3)c2)ncc1Cl |r| Show InChI InChI=1S/C29H32ClFN8O3/c1-29(2)14-22(36-28(42)39-11-4-5-12-39)26(41)35-21-13-16(9-10-18(21)29)34-27-33-15-19(30)24(38-27)37-23-17(25(40)32-3)7-6-8-20(23)31/h6-10,13,15,22H,4-5,11-12,14H2,1-3H3,(H,32,40)(H,35,41)(H,36,42)(H2,33,34,37,38)/t22-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of insulin receptor after 20 mins by time-resolved fluorescence assay |
Bioorg Med Chem 19: 6274-84 (2011)
Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J |
More data for this Ligand-Target Pair | |