BDBM50361780 CHEMBL1938516

SMILES: CC(C)[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=LFLXJKHBKXYLAD-DEOSSOPVSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50361780 (CHEMBL1938516) Show SMILES CC(C)[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H31ClN2O/c1-18(2)24(21-8-10-22(25)11-9-21)26-23(28)14-17-27-15-12-20(13-16-27)19-6-4-3-5-7-19/h3-11,18,20,24H,12-17H2,1-2H3,(H,26,28)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50361780 (CHEMBL1938516) Show SMILES CC(C)[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H31ClN2O/c1-18(2)24(21-8-10-22(25)11-9-21)26-23(28)14-17-27-15-12-20(13-16-27)19-6-4-3-5-7-19/h3-11,18,20,24H,12-17H2,1-2H3,(H,26,28)/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasma				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50361780 (CHEMBL1938516) Show SMILES CC(C)[C@H](NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H31ClN2O/c1-18(2)24(21-8-10-22(25)11-9-21)26-23(28)14-17-27-15-12-20(13-16-27)19-6-4-3-5-7-19/h3-11,18,20,24H,12-17H2,1-2H3,(H,26,28)/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair