BDBM50361907 CHEMBL1938961

SMILES: C1C2CC3CC1CC(C2)C3n1cc(nn1)-c1ccc2nccnc2c1

InChI Key: InChIKey=BQIUJAGWSXAMHA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50361907 (CHEMBL1938961) Show SMILES C1C2CC3CC1CC(C2)C3n1cc(nn1)-c1ccc2nccnc2c1 |TLB:8:7:4:2.1.0,0:1:9:6.5.4,0:5:9:2.8.1,10:9:4:2.1.0,THB:8:1:9.7.6:4,10:9:2.8.1:6.5.4,(17.39,-21.23,;15.86,-21.17,;15.56,-19.76,;16.1,-18.45,;17.59,-18.49,;18.02,-19.86,;16.83,-18.77,;15.24,-18.72,;14.62,-20.1,;14.87,-17.2,;13.34,-17.22,;12.42,-15.99,;10.96,-16.48,;10.98,-18.02,;12.45,-18.48,;9.62,-15.72,;9.62,-14.17,;8.28,-13.41,;6.95,-14.19,;5.61,-13.43,;4.28,-14.21,;4.29,-15.77,;5.64,-16.52,;6.96,-15.74,;8.3,-16.49,)| Show InChI InChI=1S/C20H21N5/c1-2-17-18(22-4-3-21-17)10-14(1)19-11-25(24-23-19)20-15-6-12-5-13(8-15)9-16(20)7-12/h1-4,10-13,15-16,20H,5-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Carna Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of FLT3 by colorimetric analysis				Bioorg Med Chem Lett 22: 591-6 (2011) Article DOI: 10.1016/j.bmcl.2011.10.076 BindingDB Entry DOI: 10.7270/Q2JQ11GW
					More data for this Ligand-Target Pair