BDBM50362086 CHEMBL1940270

SMILES: COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cn[nH]c4)cc3)c2cc1OC

InChI Key: InChIKey=YVYMHSPGVOWRQC-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50362086 (CHEMBL1940270) Show SMILES COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cn[nH]c4)cc3)c2cc1OC Show InChI InChI=1S/C21H19N5O4/c1-28-18-8-16-17(9-19(18)29-2)22-12-23-21(16)30-15-5-3-13(4-6-15)7-20(27)26-14-10-24-25-11-14/h3-6,8-12H,7H2,1-2H3,(H,24,25)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of VEGFR3 phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50362086 (CHEMBL1940270) Show SMILES COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cn[nH]c4)cc3)c2cc1OC Show InChI InChI=1S/C21H19N5O4/c1-28-18-8-16-17(9-19(18)29-2)22-12-23-21(16)30-15-5-3-13(4-6-15)7-20(27)26-14-10-24-25-11-14/h3-6,8-12H,7H2,1-2H3,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF1R phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50362086 (CHEMBL1940270) Show SMILES COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cn[nH]c4)cc3)c2cc1OC Show InChI InChI=1S/C21H19N5O4/c1-28-18-8-16-17(9-19(18)29-2)22-12-23-21(16)30-15-5-3-13(4-6-15)7-20(27)26-14-10-24-25-11-14/h3-6,8-12H,7H2,1-2H3,(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>800	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of FLT3 phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50362086 (CHEMBL1940270) Show SMILES COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cn[nH]c4)cc3)c2cc1OC Show InChI InChI=1S/C21H19N5O4/c1-28-18-8-16-17(9-19(18)29-2)22-12-23-21(16)30-15-5-3-13(4-6-15)7-20(27)26-14-10-24-25-11-14/h3-6,8-12H,7H2,1-2H3,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair