Found 3 hits for monomerid = 50362144 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50362144
(CHEMBL1940663)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C29H33N5O7S2/c1-4-19(2)27(31-20(3)35)29(37)32-22-12-10-21(11-13-22)28(36)33-43(40,41)24-14-15-25(26(18-24)34(38)39)30-16-17-42-23-8-6-5-7-9-23/h5-15,18-19,27,30H,4,16-17H2,1-3H3,(H,31,35)(H,32,37)(H,33,36)/t19-,27-/m0/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Mcl-1 by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50362144
(CHEMBL1940663)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C29H33N5O7S2/c1-4-19(2)27(31-20(3)35)29(37)32-22-12-10-21(11-13-22)28(36)33-43(40,41)24-14-15-25(26(18-24)34(38)39)30-16-17-42-23-8-6-5-7-9-23/h5-15,18-19,27,30H,4,16-17H2,1-3H3,(H,31,35)(H,32,37)(H,33,36)/t19-,27-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Bcl-2 by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 1
(Homo sapiens (Human)) | BDBM50362144
(CHEMBL1940663)Show SMILES CC[C@H](C)[C@H](NC(C)=O)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C29H33N5O7S2/c1-4-19(2)27(31-20(3)35)29(37)32-22-12-10-21(11-13-22)28(36)33-43(40,41)24-14-15-25(26(18-24)34(38)39)30-16-17-42-23-8-6-5-7-9-23/h5-15,18-19,27,30H,4,16-17H2,1-3H3,(H,31,35)(H,32,37)(H,33,36)/t19-,27-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Bcl-xL by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
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