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BDBM50362344 CHEMBL1939924

SMILES: CC1CCCCC1NC(=O)C[C@H]1N(C=CNC1=O)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=PHCAYOSMYGAILI-VMWRSERWSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50362344
PNG
(CHEMBL1939924)
Show SMILES CC1CCCCC1NC(=O)C[C@H]1N(C=CNC1=O)S(=O)(=O)c1ccc(C)cc1 |r,c:14|
Show InChI InChI=1S/C20H27N3O4S/c1-14-7-9-16(10-8-14)28(26,27)23-12-11-21-20(25)18(23)13-19(24)22-17-6-4-3-5-15(17)2/h7-12,15,17-18H,3-6,13H2,1-2H3,(H,21,25)(H,22,24)/t15?,17?,18-/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 25.9n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...


Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair