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SMILES: Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)NC1CCNc2ccccc12

InChI Key: InChIKey=VNTWPQGDVBJBNP-GFOWMXPYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362352   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM50362352
PNG
(CHEMBL1939768)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)NC1CCNc2ccccc12 |r,c:12|
Show InChI InChI=1S/C22H24N4O4S/c1-15-6-8-16(9-7-15)31(29,30)26-13-12-24-22(28)20(26)14-21(27)25-19-10-11-23-18-5-3-2-4-17(18)19/h2-9,12-13,19-20,23H,10-11,14H2,1H3,(H,24,28)(H,25,27)/t19?,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 21.6n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...

Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair