BDBM50362477 CHEMBL1940857

SMILES: Cc1ccc2cc(\C=C\C(=O)c3cc(Cl)sc3Cl)c(Cl)nc2c1

InChI Key: InChIKey=DLEVAYAWMCJTTK-SNAWJCMRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50362477 (CHEMBL1940857) Show SMILES Cc1ccc2cc(\C=C\C(=O)c3cc(Cl)sc3Cl)c(Cl)nc2c1 Show InChI InChI=1S/C17H10Cl3NOS/c1-9-2-3-10-7-11(16(19)21-13(10)6-9)4-5-14(22)12-8-15(18)23-17(12)20/h2-8H,1H3/b5-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73.4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Punjab Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay				Bioorg Med Chem Lett 22: 942-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.017 BindingDB Entry DOI: 10.7270/Q2DV1K9D
					More data for this Ligand-Target Pair