BDBM50362486 CHEMBL1940866

SMILES: Cc1cccc2cc(\C=C\C(=O)c3sccc3Cl)c(Cl)nc12

InChI Key: InChIKey=JBZJQYDDVZXTFK-AATRIKPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50362486 (CHEMBL1940866) Show SMILES Cc1cccc2cc(\C=C\C(=O)c3sccc3Cl)c(Cl)nc12 Show InChI InChI=1S/C17H11Cl2NOS/c1-10-3-2-4-11-9-12(17(19)20-15(10)11)5-6-14(21)16-13(18)7-8-22-16/h2-9H,1H3/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of the Punjab Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 after 1 hr by fluorescence polarization assay				Bioorg Med Chem Lett 22: 942-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.017 BindingDB Entry DOI: 10.7270/Q2DV1K9D
					More data for this Ligand-Target Pair