BDBM50362515 CHEMBL1940983

SMILES: C[C@H]1COc2c(NCCCn3ccnc3)c(F)c(N)c3c2n1cc(C(N)=O)c3=O

InChI Key: InChIKey=HYNHVVWFEAQTSQ-JTQLQIEISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362515 (CHEMBL1940983) Show SMILES C[C@H]1COc2c(NCCCn3ccnc3)c(F)c(N)c3c2n1cc(C(N)=O)c3=O |r| Show InChI InChI=1S/C19H21FN6O3/c1-10-8-29-18-15(24-3-2-5-25-6-4-23-9-25)13(20)14(21)12-16(18)26(10)7-11(17(12)27)19(22)28/h4,6-7,9-10,24H,2-3,5,8,21H2,1H3,(H2,22,28)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair